Model Board
Each subheading shows the most recent computational models published in each journal or preprint server. As journals publish, this page is autonomously updated and clicking the links will send you to the article.

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- Personalized Immunotherapy via Multiscale Tumor-Immune Modeling and Optimal Control
- Reversible Opto-Chemical activation of KRASG12V signaling with near single-cell precision
- Curating MitoCore: A Standardized Small-Scale Human Metabolic Model as Platform for Proteomics Integration and Disease Modeling
- A Mecom—Cdk6 toggle switch governs hematopoietic stem-to-multipotent fate transitions via distinct multistable landscapes
- Mammalian aging involves genome-wide splicing degeneration leading to functional decline
- Multi-timescale PTM architecture in human RNA polymerase II
- Spectral fingerprints distinguish buckling from angiogenesis in tortuous blood vessels
- Explaining the pathogenesis of African swine fever using knowledge-driven regulatory network modeling
- MondrianMap: Navigating Gene Set Hierarchies with Multi-Resolution Enrichment Maps
- Remodeling of the hepatic circadian transcriptome across the estrous cycle

- Identifying implementation units that would benefit from alternative treatment strategies to accelerate the elimination of onchocerciasis transmission in Africa
- Prevalence and determinants of respiratory symptoms and functional disorders among children exposed to particulate matter through domestic and maternal occupational solid fuel use in Abidjan, Cote dIvoire - a cross-sectional study
- Designing infection prevalence and seroprevalence surveys for learning infection dynamics
- A simplified antigen-based serological algorithm accurately classifies MPXV exposure and vaccination status
- Excess maternal deaths and maternal mortality ratios during the COVID-19 pandemic period: a global country-level counterfactual modelling study
- PrEP-associated screening reduces N. gonorrhoeae transmission but increases case notifications among MSM: a modeling study
- Prognostic Association of Handgrip-Defined Probable or Possible Sarcopenia Status and Polygenic Risk with 10-Year Fracture Incidence among Black, Hispanic, and White Women: A Women's Health Initiative Study
- Interaction-based metabolomics identifies serum modifiers of the clinical expression of Alzheimer's disease pathology
- Cancer trends in England in younger adults from 2001-2023: comparing incidence, mortality and stage at diagnosis
- Multi-Omic Analyses Reveal Bidirectional Genetic Links and Convergent Inflammatory-Neuronal Signatures Between Frailty, Chronic Pain, and Rheumatoid Arthritis

- Artificial intelligence for food innovation
- Towards the construction of a virtual yeast
- Interpretable spatial multi-omics data integration and dimensionality reduction with SpaMV
- RNAbpFlow: base pair-augmented SE(3) flow matching for conditional RNA 3D structure generation
- Deep residual learning for molecular force fields

- Phased variability in cell fate determination orchestrates antibody evolution
- Immune BioGraphy: A tale of graphical approaches in systems and virtual immunology
- Transcriptional competition biases the effects of second messengers in Escherichia coli
- Dango: Predicting higher-order genetic interactions
- Fusing imaging and metabolic modeling via multimodal deep learning in ovarian cancer

- Daring few, patient many: Division of labor in decentralized foraging collectives
- Modeling framework to demonstrate elimination of a vector population: Tsetse elimination in Chad
- Spatial and temporal prediction of Aedes aegypti populations with atmospheric and urban forms dependence
- Mathematical modeling of JAK2V617F clonal expansion in a general population cohort
- Correction for Zhang et al., Deep learning framework for quantifying self-organization in Myxococcus xanthus

- Collective dynamics and synchronization of coupled hair-bundle models with elastic and viscous interactions
- Varying parameter ranges alters both partial rank correlation coefficient results and phenomenological behavior when modeling the epithelial mesenchymal transition
- Adaptive social distancing under variant-specific transmission dynamics in a spatial SEIIR model with reinforcement learning
- Long-range interaction of multi-spiral cAMP waves in Dictyostelium discoideum amoeba aggregation
- A physiologically based mathematical model describing estradiol and progesterone actions on glucose-insulin dynamics throughout the menstrual cycle

- Modeling and analysis of the effect of dissolved oxygen on the dynamics of Plankton system in shallow lakes
- Simultaneous parameter and function discovery in differential equations using physics-informed neural networks
- Global dynamics of an intraguild predation predator–prey model with density-dependent velocity suppression
- Impacts of cooperative hunting and Allee effect on the dynamics of a three-species system with sexually reproducing top predators
- Optimal experiment design for practical parameter identifiability and model discrimination

- Mobility data resolution needed to inform predictive models of spatial epidemic spread from mobile phone data
- Another 10 years of PLOS Computational Biology: A data-driven reflection on trends in genomics research
- Redefining and estimating the early-phase reproduction ratio for epidemic outbreaks in spatially structured populations
- Optimized phenotype definitions boost GWAS power
- DeepMethylation: A deep learning framework for tissue-specific DNA methylation prediction and functional variant annotation

- Mathematical Modeling Shows that Overall Infection Burden is Reduced More by Vaccines that Decrease Spread or Accelerate Recovery than those that Lower Severe Infections or Death
- Identifiability, Sensitivity, and Genetic Algorithms in Bacterial Biofilm Selection Models
- Effects of Seasonal Births and Predation on Disease Spread
- Slow Evolution Towards Generalism in a Model of Variable Dietary Range
- CBINN: Cancer Biology-Informed Neural Network for Unknown Parameter Estimation and Missing Physics Identification

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- Driving biological insight from genome-scale and multiscale to whole-cell modeling
- A dialog between cell adhesion and topology at the core of morphogenesis
- Computational models of cellular bioenergetics indicate the role of Ca2+-regulated pyruvate dehydrogenase in metabolic remodeling
- Dynamics of cell fate patterning in discrete multicellular systems
- Primer: Drug discovery and patient-derived organoids

- A perception-memory PDE framework for seasonal migration dynamics
- Dynamic resource allocation in eukaryotic Resource Balance Analysis
- Spatiotemporal SEIQR Epidemic Modeling with Optimal Control for Vaccination, Treatment, and Social Measures
- Discrete-time exploitative competition model of different stage-specific predators
- Phenotypic plasticity trade-offs in an age-structured model of bacterial growth under stress
