Model Board
Each subheading shows the most recent computational models published in each journal or preprint server. As journals publish, this page is autonomously updated and clicking the links will send you to the article.

- High-fidelity and Network-based Spatio-temporal Mathematical Models of Alzheimer's Disease Progression and their Validation Against PET-SUVR Imaging Data
- Physics-Informed Neural Networks for Biological $2\mathrm{D}{+}t$ Reaction-Diffusion Systems
- How Much Data is Enough? The Zeta Law of Discoverability in Biomedical Data, featuring the enigmatic Riemann zeta function
- Noise-Driven Differentiation via Gene Frustration and Epigenetic Fixation
- Multi-Beholder: Biomarker Prediction for Low-Grade Glioma with Multiple Instance Learning and One-Class Classification
- Motif Diversity in Human Liver ChIP-seq Data Using MAP-Elites
- Spatial dynamic modelling to understand how dendritic cell clustering affects T cell activation
- MOSAIC: Codon Harmonization of Monte Carlo-Based Simulated Annealing for Linked Codons in Heterologous Protein Expression
- Poisson Flow Model of Cortical Folding Pattern
- 3D-DXA Cortical and Trabecular Parameters: Agreement Between Hologic Densitometers in Clinical Practice

- Conserved metabolic vulnerabilities across pathogenic coronaviruses nominate host-directed therapeutic targets
- SugarBase: mapping glycomolecule precursors in microbes
- Extreme genome reduction selectively retains modular regulatory architecture in Prochlorococcus MED4: conserved transcriptional modules reveal core physiological regulatory programs
- A Modular Machine Learning Framework for Small-Molecule Drug Repurposing Based on Organ Permeability, Target Binding, and Biomarker Modulation
- SEC-seq reveals translation-focused metabolic strategies for high IgG productivity in clonal CHO cells
- Orchard management alters citrus root and rhizosphere microbiomes with functional consequences for plant performance
- Serum protein profiling reveals hallmark-level aging trajectories and strain-specific resilience in CB6F1J and C57BL/6J male mice.
- Dynamic cancer dormancy and awakening emerge from tumor microenvironment feedback in a minimal theoretical model
- NovoGlyco: mapping protein glycosylation in prokaryotes
- EML4-ALK Fusion Rewires Transcriptomic, miRNA, and CAF-Associated Programs in Non-Small Cell Lung Cancer

- Mediation analysis in longitudinal data: an unbiased estimator for cumulative indirect effect
- Episia: An Open-Source Python Library for Epidemiological Surveillance, Modeling, and Biostatistics in Resource-Limited Settings
- Impact of Azithromycin Administration at Hospital Discharge on Antimicrobial Resistance and Enteropathogen Carriage 3 Months Following Treatment
- Widespread genetic effect heterogeneity impacts bias and power in nonlinear Mendelian randomization
- Validation of methods for forecasting the frequency of non-vaccine serotypes after introduction or switch of a pneumococcal conjugate vaccine
- Unscheduled bleeding and endometrial cancer in women on postmenopausal hormone replacement therapy and their matched controls: protocol for a descriptive cohort study using the Orchid-e database
- Uncovering spatial-temporal patterns in mortality counts from pulmonary embolism in US counties between 2005 to 2022.
- Loneliness as a Pathway Linking Hearing Decline to Cognitive Aging: Longitudinal and Genetic Evidence
- Association between Physical Function and Incidence of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study
- Plasma proteomics of APOE genotype: age-specific analyses in UK population-based cohorts

- Predicting RNA 3D structure and conformers using a pre-trained secondary structure model and structure-aware attention
- Generative approaches to kinetic parameter inference in metabolic networks via latent space exploration
- Data-driven mouse motor thalamus model reveals topography and spatial weight scaling govern spindle dynamics
- Dysfunction of the episodic memory network in the Alzheimer’s disease cascade
- Orthrus: toward evolutionary and functional RNA foundation models

- Engineering sensor-based antithetic integral controllers for enhanced dynamic performance and noise attenuation
- The impact of package selection and versioning on single-cell RNA-seq analysis
- NOT-gated chimeric antigen receptor circuits in T and NK cells
- Constructing a holistic map of cell fate decision by hyper solution landscape
- Systemic rhythmicity of host and bacterial bile acid amidates in the mouse

- Sparse identification of nonlinear dynamics and Koopman operators with Shallow Recurrent Decoder Networks
- Deep learning framework for quantifying self-organization in Myxococcus xanthus
- Fast automated adjoints for spectral PDE solvers
- Tracing the origin of tropical North Atlantic Sargassum blooms to West Africa
- A swarm intelligence approach to density function reconstruction from moments using entropy optimization

- A hybrid discrete-continuum modelling approach for the interactions of the immune system with oncolytic viral infections
- Vitamin C as a nitrosation inhibitor: A modelling study across dietary patterns and water quality
- Adaptive Dynamics models for the evolution of class-structured populations in stable systems
- Impacts of hunting cooperation among predators on predator-prey dynamics
- Modelling cancer cell dormancy in mice: Heavy-tailed distributions and the role of cancer cell death in reactivation times

- Persistence for a class of nonautonomous systems of differential equations with unbounded delays
- Using interconnected viscoelastic elements to investigate forces and the role of cell properties during cell migration
- A minimization principle behind the diffusion bridge of diurnal fish migration
- How mathematical forms of chemotherapy and radiotherapy bias model-optimized predictions: Implications for model selection
- Investigating the impact of adipose derived media on ovarian cancer: Insights from a 3D in-silico model

- La benchmarking large language models for extracting biobank-derived insights into health and disease
- A standardized workflow for kinetic metabolic model curation and dissemination
- Double-CRISPR Knockout Simulation (DKOsim): A Monte-Carlo randomization system to model cell growth behavior and infer the optimal library design for growth-based double knockout screens
- ‘Backpropagation and the brain’ realized in cortical error neuron microcircuits
- A phase-field model for vesicle membranes incorporating area-difference elasticity

- Statistical and Structural Bias in Birth-Death Models
- Stochastic Analysis of Taxis and Kinesis Properties of Colonial Protozoa
- A Mathematical Model for Smooth Muscle Cell Phenotype Switching In Atherosclerotic Plaque
- Macrophage Polarization Determines Inflammation Amplification and Resolution
- Vascular-Coupled Modeling of Treatment Resistance in Tyrosine Kinase Inhibitor Therapy: Parameter Estimation and Phase-Dependent Sensitivity Analysis

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- Primer: Drug discovery and patient-derived organoids
- Complex versus complicated systems biology, universality versus detailed modeling
- Simple systems, complex dynamics: Lessons from minimal gene regulatory networks
- Toward a systems view of life’s origins: Modeling the emergence of complexity across chemical, informational and ecological levels
- Intercellular coupling and synchronization of circadian clocks: Theoretical insights and experimental perspectives

- Spatiotemporal dynamics of HIV in the Brain: perspective of mathematical modeling for its control via antiretroviral therapy
- Spatio-temporal pattern formation under varying functional response parametrizations
- Effects of host migration and travel loss on strain competition in a two-patch SIR model
- Evolution of a trait distributed over a large fragmented population: propagation of chaos meets adaptive dynamics
- Trajectory inference for a branching SDE model of cell differentiation via lineage tracing